Wednesday, February 10, 2016 - 7 p.m. CET - Recording Available
In patients with metastasized non-small-cell lung cancer (NSCLC) the current typical first-line treatment approaches are four cycles cisplatin and pemetrexed in patients with non-squamous cell carcinoma. As an alternative, centers still administer carboplatin, paclitaxel and bevacizumab and these are given for four to six cycles. Strategies of maintenance chemotherapy include "switch maintenance" with changing from four cycles carbo/pacli/bev or other non-pemetrexed combinations to maintenance pemetrexed until the time of progression and "continuation maintenance" with keeping single agent pemetrexed as ongoing treatment following four cycles of cisplatin and pemetrexed. Both strategies have been shown in large prospectively randomized phase-III trials (JMEN, PARAMOUNT) to significantly improve median overall survival at about three months as well as double the median PFS at very little costs of toxicity. This strategy has since become an important option to patients for the management armamentatium of metastasized non-small-cell lung cancer without any druggable driver mutation.
Wednesday, January 27, 2016 at 9 p.m. EST - Recording Available
IASLC continues the Lung Cancer Series in 2016 with this LIVE WEBINAR featuring Dr. John Heymach.
KRAS is the most common oncogenic driver in non-small cell lung cancer and other solid tumors. Despite great rapid recent progress in the treatment other oncogene-driven malignancies, to date there are still no targeted therapies for KRAS mutant lung cancers. A major obstacle to progress in this area is the heterogeneity among different KRAS tumors. Here, we discuss how co-occurring genomic alterations impact KRAS signaling and define distinct KRAS subgroups with different drug response patterns and immune profiles, and how such an understanding of Kras subsets can lead to development of more refined therapeutic approaches.
Wednesday, January 13, 2016 - 4 p.m. GMT - Recording Available
Recent approvals of anti-PD-L1 agents for the second- and subsequent line of treatment of non-small cell lung cancer, as well emerging data with agents under active clinical evaluation mark a new era in the management of lung cancer.
Thursday, January 7, 2016 at 6 p.m. HKT - Recording Available
In this 60-minute session, this expert faculty will address the latest clinical developments and evolving standards impacting the management of advanced stage non-small cell lung cancer (NSCLC). This will be an interactive event and attendees can e-mail their questions and comments to the faculty for fruitful exchange.
Wednesday, November 18, 2015 at 9 p.m. EST - Recording Available
IASLC continues the Lung Cancer Grand Round Series in 2015 with this LIVE WEBINAR featuring Dr. Heather Wakelee.
This presentation will focus on highlights from recently presented large adjuvant trials including RADIANT, SCAT, ITACA and E1505. It will address different chemotherapy options for the adjuvant treatment of resected early stage NSCLC and review key ongoing trials looking to advance the adjuvant therapy of patients with resected NSCLC.
Tuesday, November 10, 2015 - 7 p.m. CET - Recording Available
For several decades, lung cancer has been considered a neoplastic disease affecting mainly men; however, during the past 40 years, the incidence of the disease has increased exponentially among women. Dr. Silvia Novello will cover epidemiologic changer regarding gender and lung cancer; smoking habit as the first risk factor for lung cancer also in women; lung cancer in never smokers and gender issues and present an overview on steroid hormones role in gender differences for lung cancer and other factors.
Wednesday, October 21, 2015 at 9 p.m. EDT - Recording Available
IASLC continues the Lung Cancer Grand Round Series in 2015 with this LIVE WEBINAR featuring Dr. Suresh Ramalingam.
Dr. Ramalingam will identify and discuss the key abstracts, presentations and developments reported during the recent IASLC World Conference on Lung Cancer held September 2015.