The International Association for the Study of Lung Cancer
The IASLC is a global multidisciplinary organization dedicated to eradication of all forms of lung cancer. From provision of educational events around the world and virtually to research projects and publications that advance the science of lung cancer, the IASLC's members—consisting of medical, surgical, and radiation oncologists, as well as other thoracic oncology specialists such as nurses, basic scientists, pathologists, radiologists, pulmonologists, statisticians, patient research advocates, patients, and their caregivers—are raising the bar for care of patients with lung cancer.
Understanding Treatment Options and Resistance in EGFR-positive NSCLC
Unfortunately, the inevitability of therapeutic resistance is always looming for patients with EGFR-mutated lung cancer, regardless of PD-1/PD-L1 status. Dr. Karen Reckamp—together with Drs. Ibiaya Dagogo-Jack, Ticiana Leal, and Daniel Tan, as well as patient advocate Sarah Christ—talks through a patient case, exploring all facets of the care continuum for this population. Beginning with discussion of biomarker testing and next-generation sequencing and moving through various opinions on use of whole-brain radiation therapy, combination chemotherapy, first-/second-generation TKIs, and/or osimertinib (depending on region) to other still unidentified mechanisms of resistance to EGFR TKI treatment and ongoing trials looking at novel therapeutic strategies. The ultimate goals of prolonging progression-free survival in the frontline setting and having patients living longer and better lives are reinforced in this forum. Although the patient on the case went on to the ORCHARD trial, each expert weighs in with their individual considerations for potential care paths, based on region and on emerging data.
Journal of Thoracic Oncology & JTO Clinical and Research Reports
Lung and thoracic specialists count on the IASLC’s journals to provide perspective on innovation in prevention, detention, diagnosis and cutting-edge treatments. As a leading medical journal, JTO focuses on lung and thoracic cancers and is dedicated to presenting original research reviews and opinions from a wide range of disciplines within the medical community. JTO CRR, the official open access journal of the IASLC, complements the JTO by offering authors a gold open access publication option.